Arthritis. Paracetamol found to be useless in the treatment of arthritis Paracetamol for joint inflammation

The modern rhythm of life implies the occurrence of pain from overstrain. During the day, the average working person can walk many kilometers or sit almost motionless at the monitor for a long time, performing his duties. As a result, the joints begin to become inflamed. Plagued by pain, people take paracetamol for joint pain, which really helps by having the property of slowing down inflammation.

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What is it used for

In case of joint pain, you should not immediately rush to the pharmacy to buy all the source of healing available from the pharmacist. To begin with, it is necessary to oppose all the minuses or pluses of the drug, to study the method of its use, storage, analogs, contraindications. These properties of paracetamol will be discussed in this article.

Paracetamol (20 rubles)

So, the medicine is known to us as an inexpensive antipyretic, analgesic agent, which is marketed on the pharmaceutical market in the form of tablets and suppositories. It is indicated for use in adults, children, including infants. Here it is important to correctly calculate the amount of the drug so as not to harm the patient.

Tablets, syrup, capsules, suppositories are used as one of the medicines in complex therapy. For example, in case of joint disease, the drug is taken by combining it with Diclofenac. Such an effect on the inflamed area of \u200b\u200bthe human musculoskeletal system enhances the effect of application, quickly relieves pain. Before starting treatment, be sure to talk to a qualified healthcare professional about how to take paracetamol if your joints hurt.

The medicine is taken to lower body temperature, eliminate general weakness, increased fatigue, or reduce headaches. Sometimes pediatricians recommend a pharmacological drug for young children with teething or inflammation of the child's mouth. Interestingly, an inexpensive drug relieves acne, as well as acne.

Features of reception

Doctors advise taking suppositories (suppositories) of paracetamol or as intramuscular injections. So the active substances begin their effect on the body faster, getting directly into the bloodstream. It is also important to study the question of how to take this medication in the treatment of joint pain.

Remember that when taken regularly to relieve pain or inflammation in joints and muscles, even a harmless drug such as paracetamol can be very harmful to your health.

Dosage and form of the drug

So, when taking this remedy, some basic factors should be considered. For example, the dose, form, method of administration of a pharmacological drug is of great importance. Paracetamol is known to actually help in the treatment of joints. It is only important to know the manufacturer's recommendations for use for the most effective effect on the body.

  • The medicine for young children from three months is calculated based on the weight, age of the baby. One kilogram accounts for up to ten milligrams of active ingredient. The most optimal dosage form here is suppositories.
  • For children from two to six years old, paracetamol syrup is used. The daily dose of the drug is 120-250 ml of the drug.
  • A child from six years old can be given pills, calculating half of the dosage prescribed by the doctor every four hours.
  • Children over 12 years old or adults can take no more than two tablets of the medicine at a time for joint inflammation. Treatment with medication should be short-term. In this case, the daily dose of the active substance should not exceed five hundred milliliters.

Contraindications and restrictions

Paracetamol is considered one of the most gentle, but at the same time, effective pills, suppositories or injections for the treatment of joints. But, even their reception has some features, neglect of which can lead to disastrous consequences.

  • Taking medicine for arthrosis should not exceed four days.
  • Pregnant women, nursing mothers should be careful about this remedy, despite the fact that sometimes it is considered the safest.
  • It is better for people living with high blood sugar to refuse to take the drug, since its active substance sharply lowers blood glucose levels.
  • Caution should be observed in people suffering from renal failure, liver disease, hypotension (low blood pressure).
  • You should not take paracetamol for elderly people and babies less than three months old.
  • In order to prevent an allergic reaction, before using the drug for arthritis, you should carefully study the information about its active substance, which your body may not absorb.

Paracetamol is considered a good remedy that is used as one of the components of complex therapy for relieving pain in the knee joint. It is only important to adhere to the recommended dosage for taking the drug. Before starting the application, it is imperative to study the features of using the medicine. If you know how to drink paracetamol, it will be a good helper in the fight against joint pain.

Storage and analogues

Many drugs are known that are considered analogs of paracetamol. They can only be prescribed by a doctor who is guided by the reasons for the appointment, the reaction of an individual organism to active substances, the presence of contraindications for use, etc.

The most famous analogues of paracetamol are:

  1. Panadol. The drug consists of paracetamol, caffeine, the ratio of which is designed to stop inflammation, relieve pain, and bring body temperature back to normal. Marketed as tablets, it is recommended for use only by children over 12 years of age or adults. At the same time, a person should consume no more than four grams per day.
  2. Baralgetas. Analgin and pitofeton act on the inflammation focus similarly to paracetamol. It can be used in the absence of contraindications for children or adults. It is only important to correctly calculate the amount of active ingredients, depending on the weight, as well as the age of the patient.
  3. Nimid. The basis of the pharmacological agent is nimesulide. This medicine actively fights inflammation in the joints, normalizes body temperature, and relieves pain. Usually used as tablets, granules or suspensions.

Store the drug with a good shelf life in a clean, dry place with limited sunlight. The temperature where the drug is stored should in no case exceed 25 degrees (depending on the form of release). These conditions are optimal for storing paracetamol for two to three years.

For joint pain, it is necessary to take medicines with a strong anti-inflammatory and analgesic effect. Paracetamol (paracetamol) has a pronounced antipyretic and analgesic effect, however, its anti-inflammatory activity is insufficient for pathologies of the knee joints or back diseases. This drug acts at the level of the central nervous system, therefore copes poorly with inflammatory processes in peripheral organs .

Many patients are interested in how to take Paracetamol to get rid of joint pain, because it is one of the most affordable and popular anti-inflammatory drugs. However, it is not possible to get rid of pain syndrome and inflammation with pathologies of the musculoskeletal system only with the help of Paracetamol.

How to effectively relieve pain syndrome

Paracetamol for pain in joints is most effective when combined with Diclofenac. This agent has both anti-inflammatory and analgesic effects, and the combination with Paracetamol allows you to enhance this effect. If it is not inflammation that prevails, but pain, then it is better to take such strong painkillers as Ketanov, Artoxan.

Correctly selected anti-inflammatory therapy, regimen and nutrition significantly improve the condition of patients and eliminate a number of unpleasant symptoms:

  • joint and spinal pain with or without exercise;
  • swelling and redness of the skin over the affected joints;
  • limitation of joint mobility;
  • feeling of stiffness in the morning;
  • increased body temperature;
  • general weakness and increased fatigue.
Paracetamol for joints is not the drug of choice, but it can be used as an adjunct to the main treatment. To relieve pain in arthrosis diclofenac-based ointments are widely used and other anti-inflammatory, so that you can combine local and systemic treatment of the pathological process.

- non-steroidal anti-inflammatory drug with a pronounced antipyretic effect. The medication is used advantage for the treatment of pain syndrome of moderate or low severity, accompanied by an absent inflammatory process and severe fever, body aches. The remedy is good for joint aches and signs of acute respiratory illness. Can be used to relieve headache, myalgia, neuralgia, painful periods, arthralgia, toothache. Will this medication help with arthritis or arthrosis? To find out the answer to this question, you should study the pharmacological properties of paracetamol in detail.

Pharmacological properties of Paracetamol

Paracetamol belongs to non-narcotic analgesic substances, it can be attributed to npvs only conditionally, since it relieves pain, but in fact it is not. The drug has well-pronounced antipyretic properties, there is a moderate analgesic effect, but anti-inflammatory properties are completely absent, which means that the drug will not help to calm the inflammatory process. The therapeutic effect of the drug is manifested by inhibiting inflammatory mediators, as a result of which the sensitive threshold to the perception of pain increases.

With various degenerative and inflammatory processes, paracetamol itself is unlikely to help if they are pronounced. It can be combined with other NSAIDs that are more anti-inflammatory than paracetamol itself. However, there is one option when this medication is able to help with joint pain. The fact is that most often an increase in body temperature at the initial stages of acute respiratory disease is accompanied by severe aches in the joints and muscles. This ache feels well reminiscent of a person's sore knees or other body parts. It is worth taking literally 1-2 tablets of paracetamol, as the body temperature begins to decrease, and with it the unpleasant sensation in the bones disappears.

From the above, we can conclude that paracetamol will help with joint pain, but not of an inflammatory nature, but associated with a violation of the control of thermoregulation of the body in response to the appearance of a viral agent in the patient's body. Many people will be interested in the question - which NSAIDs are best suited for dealing with pain in joints of a degenerative-inflammatory nature?

NSAIDs with pronounced anti-inflammatory properties

Arthritis is an infectious inflammation of the joint, which, in addition to the main therapy, requires symptomatic therapy to eliminate the focus of inflammation and reduce pain. Arthrosis is a chronic joint pathology, which is accompanied by limited mobility and deformity that interferes with normal motor activity. Arthrosis is accompanied by severe pain, a feeling of stiffness, especially in the morning. In addition to the main therapy, this disease requires the use of NSAIDs to relieve pain and inflammation.

The list of medicines suitable for the symptomatic treatment of arthritis and arthrosis:

  • - a non-steroidal drug with pronounced analgesic and anti-inflammatory properties, produced in the form of a gel for external use, it helps well in the presence of articular syndrome, with regular use reduces the feeling of stiffness in the morning, removes swelling, relieves pain.
  • Diclofenac sodium is a universal drug that equally has pronounced anti-inflammatory and analgesic properties. It can be used to treat pain in any location, not only in the joints. There are many forms of release, ranging from tablets, ointments and injections to rectal suppositories, transdermal patches and aerosols.
  • - a non-selective non-steroidal anti-inflammatory drug, which is prescribed mainly for the treatment of pain in degenerative processes in the joints. It is produced in the form of tablets and rectal suppositories, but due to the strong severity of side effects on the gastrointestinal tract, it is not the first choice.
  • Indometacid - NSAID in tablet form, has the most pronounced anti-inflammatory effects and moderate analgesic properties. Despite these qualities, it is rarely prescribed, due to the severity of side effects on the digestive system.
  • Movalis is a selective NSAID with moderate anti-inflammatory and analgesic properties. Due to the selective effect on pain centers, it can be used for a long time, in contrast to non-selective analogues. It is considered one of the best medications for joint pain.

Arthritis

Arthritis is called inflammation of the joints, it is a general term for a number of diseases of varying severity, different etiology and having different symptoms. They are usually characterized by moving and lifting weights. Inflammation (pain, fever, redness, or swelling) may or may not be present.

Pain, limited mobility, swelling, tenderness in any joint, neck or, are the basis for a visit to the doctor to determine the cause of these symptoms. If the doctor is not consulted for a long time, permanent damage to the joints may occur.

You should immediately get a medical examination for joint pain if:

1.joint pain or swelling occurs abruptly and is intense;

2.joint pain occurs after an injury (you may have a fracture in the joint area);

3.pain or swelling of the joint is accompanied by a fever above 380 C.

The three most common forms of arthritis are osteoarthritis and gout. Each of them is characterized by its own etiology, treatment methods and possible consequences.

Rheumatic arthritis

Rheumatic arthritis is an inflammation of the joints caused by impaired immunity; they can occur at any age. The most common victims of this disease are women, but it also occurs in children, adolescents, middle-aged and older people. often characterized by limited joint mobility in the morning, pain and swelling in the joints of the fingers, ankles, knees, wrists and elbows, and improvement occurs during the day. Joint damage is usually symmetrical, i.e. if the right knee hurts, then the left knee is also likely to be affected.

There is no radical cure for rheumatoid arthritis, but inflammation can be reduced. Drug therapy is divided into two large groups: antirheumatic drugs.

Anti-inflammatory drugs are divided into two groups: steroid and non-steroidal drugs. Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of inflammatory mediators. NSAIDs can be either salicylates like aspirin or nonsalicylates like ibuprofen (BONIFEN, BURANA).

For rheumatic arthritis, many doctors use enteric forms as the drug of choice. However, the amount of aspirin needed to reduce inflammation in arthritis creates drug concentration levels at which unwanted negative effects can occur. High-dose aspirin therapy should never be started without prior examination in order to determine the correct dose and achieve the greatest therapeutic effect with the least adverse reactions.

Aspirin has an effect at a certain level of plasma concentration, which differs from person to person. Therapeutic concentration levels of aspirin range from 15 to 30 mg per deciliter (10 liters) of blood. To reach this level, you need to take 6 to 15 regular tablets (500 mg) of aspirin (3 to 7.5 g) daily. If you are taking aspirin, you must constantly monitor the level of concentration of aspirin in the blood plasma to prevent intoxication (poisoning). Signs of aspirin poisoning include tinnitus, increased breathing (hyperventilation of the lungs), confusion, shortness of breath in the legs and ankles, increased sweating, and thirst. These symptoms should be reported to the doctor immediately.

For chronic use, such as in the treatment of rheumatoid arthritis, enteric aspirin is recommended. Studies have shown that when taking enteric forms of aspirin, the required concentration level is achieved, but the risk of stomach bleeding is sharply reduced compared to regular aspirin.

In addition to the effectiveness that characterizes all antiarthritic drugs in this group, enteric forms of aspirin are much cheaper than piroxicam. And taking piroxicam creates an increased risk of developing, bowel perforation and bleeding.

As a rule, all NSAIDs used in the treatment of rheumatoid arthritis are more expensive than aspirin, have large negative effects and are not more effective than aspirin. Like aspirin, other NSAIDs can cause gastrointestinal bleeding or renal impairment. Unless you are allergic to aspirin or have a digestive disorder while taking aspirin, enteric aspirin is the best choice for treating rheumatoid arthritis. However, if you are allergic to aspirin, or if you have digestive problems while taking aspirin, it is preferable to use another NSAID drug. Read the notes for each NSAID for recommendations for use and information on negative effects. Then select the appropriate drug for you with your doctor.

Another type of anti-inflammatory drug, steroids, are very important hormones that have two functions: regulating inflammation and controlling basic vital functions in the body. As a rule, they are not prescribed in the first stage of rheumatoid arthritis treatment. However, they can be used in older people who cannot take NSAIDs or if they do not have the desired effect. Intra-articular injection is possible if the joint is causing severe pain. It is recommended that steroids be avoided whenever possible, as they can cause a large number of negative effects, including an increased risk of increased fragility of bones (most likely in thin women with small bones).

Antirheumatic drugs. Compared to the anti-inflammatory drugs described above, antirheumatic drugs not only relieve symptoms, but can also slow down the development of the disease itself. Antirheumatic drugs such as gold salts should only be prescribed to patients who suffer from acute forms of rheumatoid arthritis and who cannot take salicylates or other NSAIDs. The latter is due to the fact that more than 50% of people taking antirheumatic drugs have some kind of toxic reaction.

Regardless of which drug you and your doctor choose for therapy, you should also develop an exercise program that is adequate for your physical condition. This will help strengthen muscles and maintain or improve joint mobility.

Inflammation can also occur in rheumatic diseases such as ankylosing spondylitis (ankylosing spondylitis), temporary arteritis, and polymyalgia rheumatica. In this case, the therapy will have the same anti-inflammatory orientation as in the treatment of rheumatoid arthritis.

Osteoarthritis

Osteoarthritis is the most common type of arthritis. It is usually associated with aging joints or past injuries. Often it is asymptomatic, sometimes there is pain and limited mobility in the joints. Osteoarthritis is usually not serious, although some people experience severe pain with limited physical capacity. In rare cases, osteoarthritis reaches a stage where walking becomes difficult. This disease often occurs in the joints of the fingers, where there are dense painless thickenings, and in the spine, where bone-like formations appear. However, all this usually does not lead to serious consequences.

Unlike rheumatoid arthritis, osteoarthritis is a degenerative joint disease that often occurs without inflammation. Excessive body weight leads to increased wear on the inner surface of the joint. Unsurprisingly, the most severe form of osteoarthritis is osteoarthritis of the joints that bear the weight of the whole body, that is, the joints of the hips and knees. Significant improvement is often seen after weight loss and an exercise program to maintain mobility in the affected joints.

Enteric aspirin is the cheapest form of pain relief in osteoarthritis. Unlike rheumatoid arthritis, which requires large doses of aspirin to relieve inflammation, two 500 mg tablets three times daily are usually sufficient to control osteoarthritis in adults. Other pain relievers, including, are recommended for those who should not take aspirin. Keep in mind that while paracetamol relieves pain compared to aspirin, it is ineffective as an anti-inflammatory agent.

Topical salicylates, which are widely advertised for the treatment of arthritis, should be used with caution. The fact is that salicylates (including) affect the joints only when dissolved in the blood, therefore, a greater effect is achieved when taking tablet forms, and not when using the drug in the form of an ointment or cream.

Physical exercise should be gentle, range of motion should be limited. Swimming and hiking are especially recommended. You can start immediately and gradually increase your strength and flexibility. Under the supervision of a physician, severe osteoarthritis is sometimes treated with physiotherapy, orthopedic devices, and in some cases, surgical intervention is indicated.

Gout

Gout is associated with the formation of uric acid crystals in the joints. White blood cells in response to the appearance of these crystals release certain enzymes into the joints. The release of these enzymes causes severe pain and inflammation during acute attacks of gout. Pain is often localized to the big toe. Treatment is necessary, as the pain usually comes on suddenly and is severe.

Treatment for gout can be divided into acute attacks and prevention of uric acid crystals. Colchicine reduces the intensity of acute attacks by suppressing the immune response of the white blood cells. NSAIDs are also effective in relieving severe attacks, but their effect becomes noticeable only after 12-24 hours. If you have frequent seizures, or if your plasma uric acid levels remain high between seizures, your doctor may prescribe allopurinol to lower your uric acid levels. reduces the production of uric acid.

People with gout should not use aspirin or other salicylates. Be aware that over-the-counter medications containing aspirin can cause uric acid retention in the body and worsen gouty arthritis. Aspirin also reduces the effectiveness of anti-gout drugs.

Infectious arthritis

Infectious arthritis occurs when bacteria enter a joint and symptoms include redness, localized fever, and swelling of the joint. It is sometimes difficult to distinguish this type of arthritis from others as they often run together.

This disease is almost always accompanied by a fever and requires in accordance with the doctor's prescription; otherwise, the infection can destroy the joint.

According to the latest scientific data, in addition to the well-known microbes that die from most antibiotics, infectious arthritis is increasingly caused and treated with a limited spectrum of antibiotics.

Alcohol is dangerous when taking pain medications

The FDA has proposed that an alcohol warning be included in the annotations of all over-the-counter pain relievers, including aspirin, other salicylates, paracetamol, ibuprofen, ketoprofen, and naproxen sodium salt.

For products containing paracetamol - "Warning about the danger of drinking alcohol: if you drink three or more alcoholic beverages a day (i.e. more than 75 ml in terms of 40% alcohol), consult your doctor if you should take the drug or other analgesic drugs. The concomitant use of alcohol and the drug may increase the risk of liver disease. "

For preparations containing aspirin, choline salicylate, ibuprofen, ketoprofen, naproxen sodium salt and sodium salicylate - "Warning about the dangers of drinking alcohol: if you drink three or more alcoholic beverages a day (i.e. more than 75 ml in terms of 40% alcohol), ask your doctor if you should take the drug or other pain relievers. Combined use may increase the risk of gastric bleeding. "

Some over-the-counter pain relievers already include warnings in their annotations.

The article used information from Sidney M. Wolf's book "Worst pills Best pills" - "Encyclopedia of Drug Safety."

Mikhail Rodinko , Andrey Sokolov,Alan Gutiev

Studying diseases of the musculoskeletal systems, doctors have established that "Paracetamol" is effective for joint pain. For the best result, other medicines prescribed by the attending physician are also taken with him. The medicine has antipyretic and anti-inflammatory effects. It is allowed to use for adults and children, taking into account the correctly calculated dosage for joint diseases.

Composition and form of release

  • The main element is paracetamol.
  • Additional elements:
    • povidone;
    • croscarmellose sodium;
    • stearic acid;
    • potato starch.

"Paracetamol" has the following forms of release:

  • syrup;
  • pills;
  • capsules;
  • suppositories.

Indications for use of the drug

"Paracetamol" is used when experiencing mild or moderate pain. These include:


The drug is effective for toothache.
  • head;
  • dental
  • joint pain;
  • pain in trauma;
  • migraine;
  • neuralgia;
  • menstrual;
  • muscle pain resulting from exertion or for no apparent reason;
  • an increase in temperature with a cold or other infectious and inflammatory processes.

Application of "Paracetamol" for the treatment of joint pain

Paracetamol is used to treat mild or moderate ailments in rheumatoid arthritis. It effectively removes pain, improving the patient's condition.

The drug is taken orally by mouth or rectally. It is necessary to follow the dosage indicated in the instructions:

  • For adults weighing over 60 kg, it is recommended to take the medicine 3-4 times a day before eating, in a period of 4-6 hours.
  • The tablet is intended for adolescents over 12 years of age. The dosage is no more than 2 tablets. per day.
  • For children 6-12 years old, the period of use will be 4 times a day with an interval of at least 6 hours.
  • At the age of 1-5 years - 120-250 ml in the form of syrup.
  • From the moment of birth to one year - 60-120 ml of suspension or rectal suppositories, the dosage of which is prescribed by the pediatrician.

Side effects and contraindications


If you take the drug longer than necessary, you may experience abdominal pain.
  • nausea;
  • stomach ache;
  • impaired liver and kidney function;
  • skin rash;
  • anemia.

Although "Paracetamol" is considered a gentle pharmaceutical preparation, even its use has limitations:

  • It is contraindicated to take capsules for people suffering from alcoholism.
  • You should take pills for arthritis no more than 4 days.
  • It is recommended that you first familiarize yourself with the substances that make up "Paracetamol" so as not to cause an allergic reaction.
  • You should not abuse the use of medicine for elderly people.
  • It is important to take the drug with caution in patients suffering from renal failure or liver disease.

Using "Paracetamol" will help reduce joint pain. It has a positive effect on the body, stopping inflammation and helping to restore health. You can buy it at any of the pharmacies without a prescription from a doctor. The choice is large, since the drug is sold in various forms, among which you can choose the most convenient. The use of the medicine does not lead to serious consequences.